C-118

Clomipramine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₁₉H₂₄Cl₂N₂
• CAS Number: 17321-77-6
• Molecular Weight: 351.31
• EC Number: 200-659-6
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: certified reference material
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in methanol (as free base)
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: clinical testing
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: Cl.CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13
• InChI: 1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
• InChI key: WIMWMKZEIBHDTH-UHFFFAOYSA-N
• 유전자 정보: human ... SLC6A4(6532)

설명

일반 설명

Clomipramine is a tricyclic antidepressant used to many conditions from major depression and panic disorder to narcolepsy and obsessive compulsion disorder (OCD). This certified solution standard is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.

애플리케이션

• Clomipramine hydrochloride solution for in vitro depression models: Research has utilized Clomipramine hydrochloride solution to develop and validate in vitro models of depression, highlighting its role as a serotonin uptake inhibitor. This aids in the pharmacokinetic profiling of antidepressants and enhances understanding of their mechanisms (Menshutina et al., 2022).
• Application in neurotransmitter research: Clomipramine hydrochloride solution has been investigated as a tricyclic antidepressant in studies of neurotransmitter systems, particularly for its high purity and effectiveness in serotonin reuptake inhibition, essential for neurotransmitter research (Teixeira Tarley et al., 2022).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup