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Merck
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LM4114

Avanti

27-hydroxycholesterol (D6)

Avanti Research™ - A Croda Brand

동의어(들):

cholest-5-ene-3β,27-diol(d6)

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C27H40D6O2
CAS Number:
1246302-95-3
Molecular Weight:
408.69
UNSPSC 코드:
12352100
NACRES:
NA.25

양식

methanol solution

포장

pkg of 1 × 1 mL (LM4114-1EA)

제조업체/상표

Avanti Research™ - A Croda Brand

농도

~10 μg/mL (Refer to C of A for lot specific concentration. )

응용 분야

lipidomics
metabolomics

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C(O)([2H])[2H])C([2H])([2H])[2H]

InChI

1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20,3)25(22)13-15-27(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t18?,19-,21+,22+,23-,24+,25+,26+,27-/m1/s1/i1D3,17D2,18D

InChI key

FYHRJWMENCALJY-CDBHVEDQSA-N

일반 설명

27-hydroxycholesterol is an abundant oxysterol in circulation.

애플리케이션

27-hydroxycholesterol (D6) or cholest-5-ene-3β,27-diol(d6) has been used as an internal standard to measure the concentration of 27-hydroxycholesterol in the pre- and post-statin-treated serum samples by mass spectrometry.

생화학적/생리학적 작용

27-hydroxycholesterol is known to induce breast cancer cell proliferation and metastatic progression in experimental models. It might serve as a ligand for liver X receptors (LXR) and farnesoid X-activated receptors (FXRs). 27-hydroxycholesterol controls the action of hydrocymethylglutaryl-CoA reductase. It promotes cholesterol efflux from the vascular endothelium.

포장

2 mL Amber Glass Sealed Ampule (LM4114-1EA)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

FlameSkull and crossbonesHealth hazard
GHS02,GHS06,GHS08

신호어

Danger

유해 및 위험 성명서

H225,H301 + H311 + H331,H370

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup

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시험 성적서(COA)

Lot/Batch Number

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