추천 제품
형태
ethanol solution
포장
pkg of 1 × 1 mL (LM2144-1EA)
제조업체/상표
Avanti Research™ - A Croda Brand
농도
~10 μg/mL (Refer to C of A for lot specific concentration.)
응용 분야
lipidomics
metabolomics
배송 상태
dry ice
저장 온도
−20°C
SMILES string
CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O
InChI
1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1
InChI key
VITGNIYTXHNNNE-LHMZYYNSSA-N
일반 설명
Sphingosine-1-phosphate (S1P) is a sphingolipid found in yeast, plants and mammals and is produced in endothelial cells. It is a cellular metabolite and signalling lipid in mammalian cells. S1P is synthesized by sphingosine kinases from sphingosine. It is a high affinity ligand for sphingosine-1-phosphate receptor (S1P1-5).
생화학적/생리학적 작용
Sphingosine 1-phosphate (S1P) plays a vital role as a secondary messenger in physiological processes. It is implicated in the pathogenesis of osteoporosis, cancer, atherosclerosis and diabetes. S1P regulates skin dendritic cells and keratinocytes
포장
2 mL Amber Glass Sealed Ampule (LM2144-1EA)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 1
Flash Point (°F)
55.4 °F - closed cup
Flash Point (°C)
13.0 °C - closed cup
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
High-Throughput Assays to Measure Intracellular Ca2+ Mobilization in Cells that Express Recombinant S1P Receptor Subtypes
Methods in Molecular Biology, 77-87 (2012)
Sphingosine-1-phosphate: an enigmatic signalling lipid
Nature Reviews in Molecular and Cell Biology, 4(5), 397-397 (2003)
Sphingosine-1-phosphate as signaling molecule in the skin
Allergo journal international, 23(2), 54-59 (2014)
Sphingosine-1-phosphate signaling and its role in disease
Trends in Cell Biology, 22(1), 50-60 (2012)
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