999995P

Edelfosine

Avanti Research^™ - A Croda Brand 999995P, powder

• 동의어(들): 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine
• 실험식(Hill 표기법): C₂₇H₅₈NO₆P
• CAS Number: 77286-66-9
• Molecular Weight: 523.73
• UNSPSC 코드: 51191904
• NACRES: NA.25

속성

• 형태: powder
• 포장: pkg of 1 × 5 mg (999995P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 999995P
• 지질 유형: cardiolipins; phospholipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC)COCCCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C10H24NO5P/c1-6-10(14-5)9-16-17(12,13)15-8-7-11(2,3)4/h10H,6-9H2,1-5H3/t10-/m0/s1
• InChI key: GVMCXWJIRSIWFJ-JTQLQIEISA-N

설명

애플리케이션

Edelfosine or 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine might be used:

• as a non-hydrolysable LysoPC (phospholipid) analog for analyzing its ability to block sexual commitment in Plasmodium falciparum
• in multilamellar vesicle preparation, to study its effect on model membranes
• in the selection and screening of mutagenized cells, having the ability to inhibit the transport of alkylphosphocholine drugs across the plasma membrane

생화학적/생리학적 작용

Edelfosine acts as a precursor for alkyl-lysophospholipids. It possesses apoptotic action against several cancer cells such as prostate, leukemia, brain and lung tumors. It is associated with cellular transport system, signaling transducing systems, cytokine synthesis and lipid metabolism. Edelfosine is known to control intracellular calcium levels. It is not mutagenic and its anti-tumor action requires its incorporation into the cell. Edelfosine is also found to block the replication of human immunodeficiency virus type I (HIV-I).

포장

5 mL Clear Glass Sealed Ampule (999995P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable