870865P

BMP22

Avanti Polar Lipids, powder

• 동의어(들): 4-pentadecylbenzylphosphonic acid
• 실험식(Hill 표기법): C₂₂H₃₉O₃P
• CAS Number: 1306684-90-1
• Molecular Weight: 382.52
• UNSPSC 코드: 12352211

속성

• 분석: 99% (TLC)
• 형태: powder
• 포장: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• 제조업체/상표: Avanti Polar Lipids
• 지질 유형: bioactive lipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

설명

일반 설명

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

생화학적/생리학적 작용

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

포장

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable