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주요 문서

860675P

Avanti

Sphinganine-1-Phosphate (d20:0)

Avanti Research - A Croda Brand 860675P, powder

동의어(들):

D-erythro-sphinganine-1-phosphate (C20 base)

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About This Item

실험식(Hill 표기법):
C20H44NO5P
CAS Number:
Molecular Weight:
409.54
UNSPSC 코드:
12352211
NACRES:
NA.25

양식

powder

포장

pkg of 1 × 1 mg (860675P-1mg)

제조업체/상표

Avanti Research - A Croda Brand 860675P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](CCCCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C20H44NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)19(21)18-26-27(23,24)25/h19-20,22H,2-18,21H2,1H3,(H2,23,24,25)/t19-,20+/m0/s1

InChI key

WEYZCBKZGOIPIU-VQTJNVASSA-N

일반 설명

Sphinganine-1-Phosphate is a phosphorylated derivative of C20 base sphinganine.

생화학적/생리학적 작용

Exogenous sphinganine-1-phosphate activates sphingosine-1-phosphate receptor 1 (S1P1). It exhibits protective effects against hepatic and renal ischemia and reperfusion (IR). Sphingosine-1 phosphate and sphinganine-1-phosphate are bioactive lipid mediators. Sphinganine-1-phosphate acts opposite to sphingosine-1 phosphate activities. Increased concentration of sphinganine-1-phosphate acts as a potential biomarker for fumonisin exposure and toxicity in mice.

포장

5 mL Amber Glass Screw Cap Vial (860675P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Sang Won Park et al.
Laboratory investigation; a journal of technical methods and pathology, 90(8), 1209-1224 (2010-05-12)
Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine-1-phosphate (S1P) levels. Furthermore, exogenous sphinganine-1-phosphate protected against both liver

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