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Key Documents

860659P

Avanti

sphingosine-1-phosphate-d7

Avanti Polar Lipids 860659P, powder

동의어(들):

D-erythro-sphingosine-d7-1-phosphate

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About This Item

실험식(Hill 표기법):
C18H31D7NO5P
CAS Number:
Molecular Weight:
386.51
UNSPSC 코드:
12352211
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 1 mg (860659P-1mg)

제조업체/상표

Avanti Polar Lipids 860659P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@]([C@]([NH3+])([H])COP([O-])(O)=O)(O)/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]

일반 설명

Sphingosine-1-phosphate (S1P) or D-erythro-sphingosine-d7-1-phosphate, is a deuterated sphingolipid. S1P, a zwitterionic sphingolipid, is an important cellular metabolite and signaling lipid in animal cells. It has also been found in insects, yeasts and plants. S1P is synthesized from the sphingosine kinase (Sph) 1 and SphK2 present in cytosol and nucleus, respectively.

애플리케이션

Sphingosine-1-phosphate (S1P)-d7 has been used as a standard in ultra-high performance liquid chromatography (UHPLC)-Q exactive for validation and quantitative analyses of S1P.

생화학적/생리학적 작용

Sphingosine-1-phosphate (S1P) plays a vital role in mammalian brain and cardiac development. It is essential for maturation of the systemic circulatory system and lymph vessels. Additionally, S1P is implicated in trafficking and effector functions of lymphocytes and other blood stem cells. It also provides protection against various forms of tissue injury. S1P also acts as a tumor promoting lipid. S1P has an ability to enhance erythrocyte glycolysis and oxygen delivery therefore, it can be used to treat tissue hypoxia.

포장

5 mL Amber Glass Screw Cap Vial (860659P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

또한 이 제품과 함께 일반적으로 구입

Storage Class Code

11 - Combustible Solids

Flash Point (°F)

No data available

Flash Point (°C)

No data available


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia
Sun K, et al.
Nature Communications, 7(7), 12086-12086 (2016)
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Sun K, et al.
Scientific reports, 7(1), 15281-15281 (2017)
An update on sphingosine-1-phosphate and other sphingolipid mediators
Fyrst H and Saba JD
Nature Chemical Biology, 6(7), 489-489 (2010)
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