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Merck
모든 사진(2)

Key Documents

860080P

Avanti

18:1 Lactosyl PE

Avanti Research - A Croda Brand

동의어(들):

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)

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About This Item

실험식(Hill 표기법):
C53H103N2O18P
CAS Number:
Molecular Weight:
1087.36
UNSPSC 코드:
51191904
NACRES:
NA.25

설명

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-lactosyl (ammonium salt)

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 25 mg (860080P-25mg)
pkg of 1 × 5 mg (860080P-5mg)
pkg of 1 × 50 mg (860080P-50mg)

제조업체/상표

Avanti Research - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP(OCCNCC(O)C(O)[C@@H]([C@H](O)CO)O[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

InChI

1S/C53H100NO18P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-46(59)67-40-42(70-47(60)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)41-69-73(65,66)68-36-35-54-37-43(57)48(61)52(44(58)38-55)72-53-51(64)50(63)49(62)45(39-56)71-53;/h17-20,42-45,48-58,61-64H,3-16,21-41H2,1-2H3,(H,65,66);1H3/b19-17-,20-18-;/t42-,43?,44?,45?,48?,49+,50?,51?,52-,53+;/m1./s1

InChI key

POKKWVSABAYGGQ-GDPHZLNSSA-N

일반 설명

Phosphatidylethanolamine is a phospholipid and is bound to the biological membranes.

애플리케이션

18:1 Lactosyl PE is suitable for the preparation of donor liposomes.

생화학적/생리학적 작용

Phosphatidylethanolamine has a tendency of binding to proteins and forming a complex of phosphatidylethanolamine-binding protein (PEBP). The binding of an isoform of phosphatidylethanolamine (1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine) to Peroxisome Proliferator-Activated Receptors (PPARs) helps in regulating genes involved in lipid metabolism.

포장

5 mL Clear Glass Sealed Ampule (860080P-25mg)
5 mL Clear Glass Sealed Ampule (860080P-50mg)
5 mL Clear Glass Sealed Ampule (860080P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction
Banfield M J, et al.
Structure, 6(10), 1245-1254 (1998)
A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7
Bockelmann S, et al.
Journal of Lipid Research, 59(3), 515-530 (2018)
Phosphatidylcholine?s functions beyond that of a membrane brick
Furse S and De Kroon AIPM
Molecular Membrane Biology, 32(4), 117-119 (2015)
Svenja Bockelmann et al.
Journal of lipid research, 59(3), 515-530 (2018-01-19)
Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction

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