추천 제품
설명
1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
분석
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
형태
powder
포장
pkg of 1 × 200 mg (857123P-200mg)
pkg of 1 × 25 mg (857123P-25mg)
제조업체/상표
Avanti Research™ - A Croda Brand
지질 유형
phospholipids
cardiolipins
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.
애플리케이션
16:0 Lyso PA is suitable to use as an internal standard to extract lipids from plasma sample of ovarian cancer patients. It is also suitable for the preparation of lipid solutions for synthesizing liposomes.
생화학적/생리학적 작용
Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca2+ mobilization, neurotransmitter release and cell proliferation. Palmitoyl-lysophosphatidic acid helps in increasing aggregation, stimulated by adenosine diphosphate (ADP).
포장
5 mL Amber Glass Screw Cap Vial (857123P-200mg)
5 mL Amber Glass Screw Cap Vial (857123P-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling
Cellular Signalling, 32(1-2), 66-75 (2017)
Are lysophosphatidic acids or phosphatidic acids involved in stimulus activation coupling in platelets
Blood, 60(3), 642-649 (1982)
Langmuir : the ACS journal of surfaces and colloids, 36(17), 4671-4681 (2020-04-10)
Amyloid fibrils are formed by denatured proteins when the supersaturation of denatured proteins is broken by agitation, such as ultrasonication, or by seeding, although the detailed mechanism of how solubility and supersaturation regulate amyloid formation remains unclear. To further understand
Scientific reports, 5, 13343-13343 (2015-08-14)
Lysophosphatidic acid (LPA) receptor 1 (LPA1) is a member of the G protein-coupled receptors mediating the biological response to LPA species. Lack of detailed mechanism underlying LPA/LPA1 interaction has hampered the development of specific antagonists. Here, novel N-terminal Lys39 has
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
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