추천 제품
분석
>99% (TLC)
양식
liquid
포장
pkg of 1 × 1 mL (840030C-10mg)
pkg of 1 × 2.5 mL (840030C-25mg)
제조업체/상표
Avanti Research™ - A Croda Brand 840030C
농도
10 mg/mL (840030C-10mg)
10 mg/mL (840030C-25mg)
지질 유형
phospholipids
cardiolipins
배송 상태
dry ice
저장 온도
−20°C
SMILES string
[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O.[Na+]
InChI
1S/C18H34NO10P.Na/c1-3-5-7-9-16(20)26-11-14(29-17(21)10-8-6-4-2)12-27-30(24,25)28-13-15(19)18(22)23;/h14-15H,3-13,19H2,1-2H3,(H,22,23)(H,24,25);/q;+1/p-1/t14-,15+;/m1./s1
InChI key
OPDYVXCKOQKYDZ-LIOBNPLQSA-M
일반 설명
Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules like bone, enamel and dentin.
애플리케이션
06:0 PS may be used:
- to study its effect on α-syn (α-synuclein) oligomerization by DA (dopamine)
- to prepare phosphatidylserine (PS) liposomes
- as a phospholipid substrate to determine the kinetic parameters for phospholipase C by chromogenic assay
생화학적/생리학적 작용
Phosphoserine (PS) can be used as a template moiety for the recognition of cancer antigen 125 (CA 125). It is essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans and is blood-brain barrier traversable. PS actively participates in the locomotor functions.
포장
5 mL Clear Glass Sealed Ampule (840030C-10mg)
5 mL Clear Glass Sealed Ampule (840030C-25mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
표적 기관
Central nervous system
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
Athena Sudom et al.
The Journal of biological chemistry, 293(32), 12634-12646 (2018-05-26)
Triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor expressed on the surface of microglia, macrophages, dendritic cells, and osteoclasts. The R47H TREM2 variant is a significant risk factor for late-onset Alzheimer's disease (AD), and the molecular
Chi L L Pham et al.
Bioscience reports, 33(5) (2013-09-27)
The deposition of α-syn (α-synuclein) as amyloid fibrils and the selective loss of DA (dopamine) containing neurons in the substantia nigra are two key features of PD (Parkinson's disease). α-syn is a natively unfolded protein and adopts an α-helical conformation
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly
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