810603C

16:0-10 Doxyl PC

Avanti Research^™ - A Croda Brand 810603C

• 동의어(들): 1-palmitoyl-2-stearoyl-(10-doxyl)-sn-glycero-3-phosphocholine
• 실험식(Hill 표기법): C₄₆H₉₀N₂O₁₀P
• CAS Number: 188004-25-3
• Molecular Weight: 862.19
• UNSPSC 코드: 41141825
• NACRES: NA.12

속성

• 분석: >99% (TLC)
• 형태: liquid
• 포장: pkg of 1 × 1 mL (810603C-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 810603C
• 농도: 1 mg/mL (810603C-1mg)
• 지질 유형: ESR probes; phospholipids
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine metabolism.

애플리케이션

16:0-10 Doxyl PC may be used in vesicles for quenching PT-(1–46)F4W fluorescence. It may also be used in vesicles to check the fluorescence emission spectra in order to measure the penetration depth of the peptides′ tryptophan residues in lipid bilayer.

생화학적/생리학적 작용

Phosphatidylcholine (PC) lowers the levels of cholesterol and triglycerides.

포장

5 mL Clear Glass Sealed Ampule (810603C-1mg)

제조 메모

Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 예방조치 성명서: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 표적 기관: Central nervous system, Liver,Kidney
• WGK: WGK 3