810280P
Avanti
TopFluor™ Lyso PA
Avanti Research™ - A Croda Brand 810280P, powder
동의어(들):
1-{12-[4-(dipyrrometheneboron difluoride)butanoyl]amino}dodecanoyl-2-hydroxy-sn-glycero-3-phosphate (ammonium salt)
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C32H54BF2N4O8P
CAS Number:
Molecular Weight:
702.57
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
분석
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
형태
powder
포장
pkg of 1 × 1 mg (810280P-1mg)
제조업체/상표
Avanti Research™ - A Croda Brand 810280P
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Lysophosphatidic acid (LPA) is a water-soluble, bioactive phospholipid. It is seen in mammalian cells and tissues, including blood. LPA is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.
애플리케이션
TopFluor™ Lyso PA may be used as the chromophore and as a component in the formation of the Langmuir-Blodgett (LB) film.
생화학적/생리학적 작용
Lysophosphatidic acid (LPA) is very essential in signaling. It may alter proliferation, survival, cytoskeletal changes and calcium influx. It plays a key role in neointimal formation, endothelium dysfunction, monocyte attraction and adhesion.
포장
5 mL Amber Glass Screw Cap Vial (810280P-1mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Lysophosphatidic acid triggers apoptosis in HeLa cells through the upregulation of tumor necrosis factor receptor superfamily member 21
Dong Y, et al.
Mediators of Inflammation (2017)
Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21
Dong Y, et al.
Mediators of Inflammation (2017)
Diffusional motion as a gauge of fluidity and interfacial adhesion. Supported alkylphosphonate monolayers
Baumler SM, et al.
Journal of Colloid and Interface Science, 468, 145-155 (2016)
Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance
Lin ME, et al.
Prostaglandins & other lipid mediators, 91(3-4), 130-138 (2010)
Lauren P Saunders et al.
The Journal of biological chemistry, 286(34), 30130-30141 (2011-07-02)
Autotaxin (ATX) is a secreted lysophospholipase D that hydrolyzes lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), initiating signaling cascades leading to cancer metastasis, wound healing, and angiogenesis. Knowledge of the pathway and kinetics of LPA synthesis by ATX is critical for
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