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Merck
모든 사진(2)

Key Documents

810120P

Avanti

18:0 PEG2000 PE CF

Avanti Research - A Croda Brand

동의어(들):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (ammonium salt)

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About This Item

CAS Number:
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

포장

pkg of 1 × 1 mg (810120P-1mg)
pkg of 1 × 500 μg (810120P-500ug)

제조업체/상표

Avanti Research - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

일반 설명

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (18:0 PEG2000 PE CF) lipid comprises hydrophilic polyethylene glycol (PEG) polymer in its head groups. DSPE-PEG(2000) micelles exist as spheroid in aqueous solution.

애플리케이션

18:0 PEG2000 PE CF may be used:
  • in in vitro release assays from nanoemulsion (NE)
  • for the labeling PEGylated LPD (liposome-polycation-DNA) for size exclusion chromatography studies
  • as a fluorescent probe to monitor shape transformation in giant vesicles

생화학적/생리학적 작용

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (18:0 PEG2000 PE CF) micelles aid in nanoparticles based drug delivery. It has potential to solubilize hydrophobic drugs and aid in the controlled release of drugs. 18:0 PEG2000 PE CF also called the DSPE−PEG2000, prevents the uptake of drugs by mononuclear phagocyte system and is a potential drug carrier for cancer therapy.

포장

5 mL Clear Glass Sealed Ampule (810120P-1mg)
5 mL Clear Glass Sealed Ampule (810120P-500ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Repeated injections of PEG-PE liposomes generate anti-PEG antibodies
Sroda K, et al.
Cellular & Molecular Biology Letters, 10, 37-47 (2005)
Shape Transformations of Lipid Vesicles by Insertion of Bulky-Head Lipids
Tsuda S, et al.
PLoS ONE, 10(7), e0132963-e0132963 (2015)
Nanoparticles evading the reticuloendothelial system: role of the supported bilayer
Li SD and Huang L
Biochimica et Biophysica Acta - Biomembranes, 1788(10), 2259-2266 (2009)
Yasuhiro Kakimoto et al.
Langmuir : the ACS journal of surfaces and colloids, 34(24), 7201-7209 (2018-05-24)
Lipid molecules such as glycolipids that are modified with hydrophilic biopolymers participate in the biochemical reactions occurring on cell membranes. Their functions and efficiency are determined by the formation of microdomains and their physical properties. We investigated the morphology and

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