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모든 사진(1)

문서

710341C

Avanti

16:0-18:1 Cardiolipin

Avanti Research - A Croda Brand

동의어(들):

1′,3′-bis[1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho]-glycerol, sodium salt

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About This Item

실험식(Hill 표기법):
C77H144Na2O17P2
CAS Number:
Molecular Weight:
1449.88
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

chloroform solution

포장

pkg of 1 × 2.5 mL (710341C-25MG)

제조업체/상표

Avanti Research - A Croda Brand

농도

10 mg/mL in chloroform (710341C-25MG)

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

O=P([O-])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)OCC([H])(O)COP([O-])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O.[Na+].[Na+]

일반 설명

Cardiolipin is a 1,3-diphosphatidyl-sn-glycerol, a homodimeric phospholipid with four fatty acids. Cardiolipin is unique because of its atypical fatty acid composition. It is present in the mitochondrial membrane. CL species are complex in structure and several permutations exists due to variations in the chain length, degree of unsaturation, as well as combinations of four fatty acid substituents.

생화학적/생리학적 작용

Cardiolipin is a specific marker of mitochondria and is essential for multiple roles like energy transformation, apoptosis, and membrane integrity. 16:0-18:1 is a nascent cardiolipin acts as a precursor for the synthesis of tetralinoleoyl cardiolipin (TLCL).

포장

5 mL Amber Glass Screw Cap Vial (710341C-25MG)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Molecular symmetry in mitochondrial cardiolipins
Schlame M, et al.
Chemistry and Physics of Lipids, 138(1-2), 38-49 (2005)
The phospholipase iPLA2gamma is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling
Liu GY, et al.
The Journal of Biological Chemistry, 292(25), 10672-10684 (2017)
Characterization of cardiolipin as the sodiated ions by positive-ion electrospray ionization with multiple stage quadrupole ion-trap mass spectrometry
Hsu FF and Turk J
Journal of the American Society For Mass Spectrometry, 17(8), 1146-1157 (2006)
Marina Pinheiro et al.
Membranes, 9(11) (2019-11-02)
This work focuses on the interaction of the novel and representative antituberculosis (anti-TB) drug bedaquiline (BDQ) with different membrane models of eukaryotic and prokaryotic cells. The effect of BDQ on eukaryotic cell membrane models was assessed using liposomes, namely, multilamellar
Hannah Cetuk et al.
Langmuir : the ACS journal of surfaces and colloids, 36(18), 5065-5077 (2020-04-21)
Piscidins 1 and 3 (P1 and P3) are potent antimicrobial peptides isolated from striped bass. Their mechanism of action involves formation of amphipathic α-helices on contact with phospholipids and destabilization of the microbial cytoplasmic membrane. The peptides are active against

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