추천 제품
분석
>99% (TLC)
형태
powder
포장
pkg of 1 × 10 mg (700172P-10mg)
제조업체/상표
Avanti Polar Lipids 700172P
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Cholesterol-d6 is a deuterium labelled cholesterol. Ring labelled D6-cholesterol forms D6-steroidal glycoalkaloids (SGA).
Cholesterol-d6 is the deuterated cholesterol with deuteration in ring.
애플리케이션
Cholesterol-d6 is suitable for its use as a synthetic lipid standard, for cholesterol determination.
Cholesterol-d6 is used as a standard to detect cholesterol concentration using chromatography technique. It is also used to measure the percentage of cholesterol absorption by intravenously administrating into experimental animals.
Cholesterol-d6 may be used as an internal standard in
- electrospray ionization tandem mass spectrometry (ESIMS/MS)
- gas chromatography–mass spectrometry (GC-MS)
- for spiking lipid extracts from Drosophila for liquid chromatography–mass spectrometry (LC-MS)
생화학적/생리학적 작용
Cholesterol-d6 rich liposomes are used in understanding the kinetics of reverse cholesterol transport in lymphatic and aorta. It is used in the generation of stratum corneum (SC) lipid model systems for deuteration based neutron diffraction studies. Use of Cholesterol-d6 as a diet supplement has enabled the understanding cholesterol metabolism in the blood brain barrier.
포장
5 mL Amber Glass Screw Cap Vial (700172P-10mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Biochemical membrane lipidomics during Drosophila development
Guan XL, et al.
Developmental Cell, 24(1), 98-111 (2013)
Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris
Moulin M, et al.
Chemistry and Physics of Lipids, 212, 80-87 (2018)
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice
Martel C, et al.
The Journal of Clinical Investigation, 123(4), 1571-1579 (2013)
Cholesterol and Other Lipid Metabolism
Stable Isotope Characterization of TICs/TIMs: Analytical Progress Report. No. LLNL-TR-413939. Lawrence Livermore National Laboratory (LLNL), Livermore, CA, 2009., 157-157 (2003)
Localisation of partially deuterated cholesterol in quaternary SC lipid model membranes: a neutron diffraction study
Kessner D, et al.
European Biophysics Journal, 37(6), 1051-1057 (2008)
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