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Merck
모든 사진(2)

주요 문서

700133P

Avanti

3β,25-OH-7-oxo-5-cholestenoic acid

Avanti Polar Lipids 700133P, powder

동의어(들):

3β,25-dihydroxy-7-oxo-5-cholestenoic acid

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About This Item

실험식(Hill 표기법):
C27H42 O5
CAS Number:
Molecular Weight:
446.62
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 mg (700133P-1mg)

제조업체/상표

Avanti Polar Lipids 700133P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

O[C@H](C1)CC[C@](C1=C[C@H]2O)(C)C3C2C(CC[C@@H]4[C@H](C)CCCC(C)(O)CO)[C@]4(C)CC3

일반 설명

3β,25-OH-7-oxo-5-cholestenoic acid is a cholesterol derivative and an oxysterol derived from cholesterol. The synthesis of CA occurs in mitochondria and the enzyme sterol 27-hydroxylase (CYP27A1) catalyzes the step.

생화학적/생리학적 작용

Cholestenoic acid (CA) serves as a ligand to nuclear receptor and may be neurotoxic or neuroprotective based on their structural features. Defects in the enzymes catalyzing the formation of cholestenoic acids are implicated in disorders related to motor neuron degeneration.

포장

5 mL Amber Glass Screw Cap Vial (700133P-1mg)

Storage Class Code

11 - Combustible Solids


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Cholestenoic acid is a prognostic biomarker in acute respiratory distress syndrome.
Jennifer H Madenspacher et al.
The Journal of allergy and clinical immunology, 143(1), 440-442 (2018-10-09)
Peter J Crick et al.
The Journal of steroid biochemistry and molecular biology, 195, 105475-105475 (2019-09-22)
While the presence and abundance of the major oxysterols and cholestenoic acids in the circulation is well established, minor cholesterol metabolites may also have biological importance and be of value to investigate. In this study by observing the metabolism of

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