700070P

trihydroxycholestanoic acid

Avanti Research^™ - A Croda Brand

• 동의어(들): 3α,7α,12α-trihydroxycholestanoic acid
• 실험식(Hill 표기법): C₂₇H₄₆O₅
• CAS Number: 547-98-8
• Molecular Weight: 450.65
• MDL number: MFCD23103336
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (700070P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 지질 유형: bile acids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: O[C@H]1[C@@H]2[C@@H]([C@@]4([C@H](C1)C[C@@H](CC4)O)C)C[C@@H]([C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(C)C(=O)O)C)C)O
• InChI: 1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1
• InChI key: CNWPIIOQKZNXBB-VCVMUKOKSA-N

설명

일반 설명

Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.

애플리케이션

Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein.

생화학적/생리학적 작용

Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase.

포장

5 mL Amber Glass Screw Cap Vial (700070P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): No data available
• Flash Point (°C): No data available