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Merck
모든 사진(1)

문서

W239607

Sigma-Aldrich

Dimethyl succinate

98%, FG

동의어(들):

Dimethyl butanedioate, Succinic acid dimethyl ester

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About This Item

Linear Formula:
CH3OCOCH2CH2COOCH3
CAS Number:
Molecular Weight:
146.14
FEMA Number:
2396
Beilstein:
956776
EC Number:
유럽평의회 번호:
439
MDL number:
UNSPSC 코드:
12164502
PubChem Substance ID:
플래비스(Flavis) 번호:
9.445
NACRES:
NA.21

생물학적 소스

synthetic

Quality Level

Grade

FG
Halal
Kosher

규정 준수

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

vapor pressure

0.3 mmHg ( 20 °C)

분석

98%

autoignition temp.

689 °F

expl. lim.

8.5 %

refractive index

n20/D 1.419 (lit.)

bp

200 °C (lit.)

mp

16-19 °C (lit.)

density

1.117 g/mL at 25 °C (lit.)

응용 분야

flavors and fragrances

문건

see Safety & Documentation for available documents

식품 알레르기항원

no known allergens

감각 수용성의

green; fruity; floral; sweet

SMILES string

COC(=O)CCC(=O)OC

InChI

1S/C6H10O4/c1-9-5(7)3-4-6(8)10-2/h3-4H2,1-2H3

InChI key

MUXOBHXGJLMRAB-UHFFFAOYSA-N

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일반 설명

Dimethyl succinate can be used as a flavoring agent in the food industry.

애플리케이션


  • Metabolic Bypass Rescues Aberrant S-nitrosylation-Induced TCA Cycle Inhibition and Synapse Loss in Alzheimer′s Disease Human Neurons.: This research discusses the role of metabolic intermediates like Dimethyl succinate in bypassing biochemical blocks in Alzheimer′s disease, offering potential therapeutic avenues (Andreyev et al., 2024).

  • Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-0.: A comprehensive safety assessment of Dimethyl succinate as a fragrance ingredient, highlighting its toxicological profile and safe usage parameters (Api et al., 2023).

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

201.2 °F - closed cup

Flash Point (°C)

94 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


시험 성적서(COA)

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문서 라이브러리 방문

Burdock, GA
Encyclopedia of Food and Color Additives, 1, 878-879 (1997)
L Ladriere et al.
JPEN. Journal of parenteral and enteral nutrition, 20(4), 251-256 (1996-07-01)
Succinic acid dimethyl ester (SAD) is efficiently metabolized in several cell types as pancreatic islet cells, hepatocytes, and colonocytes. The purpose of this study was to assess the overall nutritional value of SAD in the whole organism. SAD was infused
André Mukala-Nsengu et al.
Biochemical pharmacology, 67(5), 981-988 (2004-04-24)
The relative contribution of glycolysis vs. oxidative metabolism to the stimulus secretion coupling mechanism of beta-cells was investigated in isolated islets. For that purpose, the secretory and intracellular calcium responses of islets to both glucose and succinic acid dimethyl ester
Lili Yang et al.
The Journal of biological chemistry, 283(32), 21978-21987 (2008-06-12)
We conducted a study coupling metabolomics and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. Rat livers were perfused with lactate or pyruvate +/- aminooxyacetate or mercaptopicolinate in the presence of 40% enriched NaH(13)CO(3). Other livers were perfused
J Cancelas et al.
International journal of molecular medicine, 8(3), 269-271 (2001-08-09)
It was recently proposed that suitable succinic acid esters could be used to potentiate the insulinotropic action of glucagon-like peptide 1 (GLP-1) in the treatment of type-2 diabetes mellitus. In such a perspective, the present study aimed mainly at investigating

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