QBD10275

MAL-dPEG^®₈-acid

>95% (HPLC)

• 동의어(들): Carboxy-PEG-maleimide, Carboxy-PEG₈-maleimide, MAL-PEG₄₀₀-acid, MAL-PEG₈-COOH, MAL-PEG₈-acid
• 실험식(Hill 표기법): C₂₆H₄₄N₂O₁₃
• Molecular Weight: 592.63
• MDL number: MFCD13184956
• UNSPSC 코드: 12352106
• NACRES: NA.22

속성

• 분석: >95% (HPLC)
• 양식: solid or viscous liquid
• 반응 적합성: reaction type: Pegylations
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: N1(C(=O)C=CC1=O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

설명

특징 및 장점

MAL-dPEG₈-acid is a monodisperse crosslinker that joins sulfhydryl groups to free amines through a single molecular weight polyethylene glycol (PEG) chain of discrete length. The linker is 34 atoms and 38.8 Å long. The maleimidopropyl moiety reacts with sulfhydryl groups via a Michael addition reaction. The propionic acid terminus of the molecule reacts directly with free amines using EDC or another carbodiimide to form amide bonds. Alternatively, activation of the propionic acid group with N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), or some other acylating agent permits amide bond formation under mild, controlled conditions.

법적 정보

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable