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Merck
모든 사진(1)

주요 문서

D186252

Sigma-Aldrich

N,N-Dimethylsulfamoyl chloride

99%

동의어(들):

Dimethylamidosulfonyl chloride, Dimethylaminosulfonyl chloride, Dimethylsulphamoyl chloride, N,N-Dimethylamidosulfonyl chloride, N,N-Dimethylaminosulfonyl chloride, N,N-Dimethylsulfamoyl chloride, N,N-Dimethylsulfamyl chloride

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About This Item

Linear Formula:
(CH3)2NSO2Cl
CAS Number:
Molecular Weight:
143.59
Beilstein:
741979
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

분석

99%

양식

liquid

refractive index

n20/D 1.452 (lit.)

bp

114 °C/75 mmHg (lit.)

density

1.337 g/mL at 25 °C (lit.)

SMILES string

CN(C)S(Cl)(=O)=O

InChI

1S/C2H6ClNO2S/c1-4(2)7(3,5)6/h1-2H3

InChI key

JFCHSQDLLFJHOA-UHFFFAOYSA-N

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애플리케이션

Applications of N,N -dimethylsulfamoyl chloride are:
  • It is widely used in the synthesis of a medicinally important class of compounds, sulfonamides.
  • It is used in the synthesis of aminotetralin derived sulfamides as anticancer agents and acetylcholinesterase inhibitors.
  • It can also be used in the esterification/amidation between carboxylic acids and equimolar amounts of alcohols/amines, as in the synthesis of coumaperine.

픽토그램

Skull and crossbonesHealth hazardCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

149.0 °F - closed cup

Flash Point (°C)

65 °C - closed cup

개인 보호 장비

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Synthesis and Anticancer Activity of Novel Ureas and Sulfamides Incorporating 1-Aminotetralins.
Ozgeris B, et al.
Archives of Medical Research (2017)
Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds.
Ozgeris B, et al.
Bioorganic & Medicinal Chemistry, 24(10), 2318-2329 (2016)
Novel and efficient method for esterification, amidation between carboxylic acids and equimolar amounts of alcohols, and amines utilizing Me2NSO2Cl and N, N-dimethylamines; its application to the synthesis of coumaperine, a natural chemopreventive dieneamide.
Wakasugi K, et al.
Tetrahedron, 59(28), 5337-5345 (2003)
Catalytic arylation of sulfamoyl chlorides: A practical synthesis of sulfonamides.
Frost CG, et al.
Synlett, 2002(11), 1928-1930 (2002)

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