추천 제품
![2-{2-[(2-Bromo-6-chlorophenyl)amino]phenyl}acetic acid pharmaceutical impurity standard](/deepweb/assets/sigmaaldrich/product/structures/303/197/4983f71e-abfb-4dc7-b1e9-0446b7f2c476/640/4983f71e-abfb-4dc7-b1e9-0446b7f2c476.png)
양식
solid
광학 활성
[α]/D +69.5°, c = 0.4 in H2O(lit.)
반응 적합성
reaction type: solution phase peptide synthesis
색상
off-white
solubility
H2O: soluble
응용 분야
peptide synthesis
SMILES string
[H][C@]1(C[C@@H]1C(O)=O)[C@H](N)C(O)=O
InChI
1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1
InChI key
GZOVEPYOCJWRFC-UZBSEBFBSA-N
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생화학적/생리학적 작용
Potent NMDA receptor agonist.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
Cynthia Levinthal et al.
Pharmacology, 83(2), 88-94 (2008-12-10)
Protons act as neuromodulators and produce significant effects on synaptic transmission. The molecular basis of neuromodulation by extracellular protons is partially explained by their effects on certain neurotransmitter receptors and ion channels. The metabotropic glutamate receptors (mGluRs) are a family
Maria Smiałowska et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 32(6), 1242-1250 (2006-11-30)
Earlier studies conducted by our group and by other authors indicated that metabotropic glutamatergic receptor (mGluR) ligands might have anxiolytic activity and that amygdalar neuropeptide Y (NPY) neurons were engaged in that effect. Apart from the amygdala, the hippocampus, another
Timo Kirschstein et al.
Neuropharmacology, 47(2), 157-162 (2004-06-30)
Specific agonists of metabotropic glutamate receptors (mGluRs) provide powerful tools to discriminate afferent fibers originating from different presynaptic neurons. The group II mGluR agonists L-CCG-I ((2S,1'S,2'S)-2-(2-carboxycyclopropyl)glycine) and DCG-IV ((2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine) are commonly used to distinguish between mossy fiber and associational-commissural (A/C)
Ke-Zhong Shen et al.
The Journal of physiology, 553(Pt 2), 489-496 (2003-09-23)
Patch pipettes were used to record currents in whole-cell configuration to study the effects of group II metabotropic glutamate receptor (mGluR) stimulation on synaptic transmission in slices of rat subthalamic nucleus. Evoked glutamatergic excitatory postsynaptic currents (EPSCs) were reversibly reduced
Pradeep Kumar et al.
Organic & biomolecular chemistry, 10(34), 6987-6994 (2012-07-27)
An efficient high yielding improved method for the enantio- and diastereoselective cyclopropanation of chiral epoxides using triethylphosphonoacetate and base (Wadsworth-Emmons cyclopropanation) is reported. The utility of this protocol is illustrated by concise and practical synthesis of cascarillic acid, grenadamide and
문서
Our new product range of pharmaceutical impurity solutions as certified reference materials (CRMs) save costs and labor by providing all impurities listed in the USP as well as in the EP in one mix.
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