ALD00420

2-cyanophenyl sulfofluoridate

• 실험식(Hill 표기법): C₇H₄FNO₃S
• Molecular Weight: 201.17
• UNSPSC 코드: 12352100
• PubChem Substance ID: 329772673
• NACRES: NA.22

속성

• 형태: liquid
• Quality Level: 100
• SMILES string: O=S(F)(OC1=CC=CC=C1C#N)=O
• InChI: 1S/C7H4FNO3S/c8-13(10,11)12-7-4-2-1-3-6(7)5-9/h1-4H
• InChI key: FWHISILUCPTNBH-UHFFFAOYSA-N

설명

일반 설명

2-Cyanophenyl sulfofluoridate is an aryl fluorosulfate. It undergoes Suzuki-Miyaura reaction with aryl boronic acid in the presence of Pd(OAc)₂ and Et₃N to afford the corresponding biaryl derivative. 2-Cyanophenyl sulfofluoridate can be synthesized from the reaction between phenol and sulfuryl fluoride in the presence of triethylamine.

애플리케이션

The following aryl fluorosulfate can be utilized as a cross-coupling partner in Suzuki-Miyaura reactions. The standard reaction conditions for these palladium-catalyzed C-C bond formations are ligand-free and can be performed in water, at room temperatre and are not air sensitive.

기타 정보

Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P280 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable