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Merck
모든 사진(1)

Key Documents

A47052

Sigma-Aldrich

6-Aminochrysene

95%

동의어(들):

6-Chrysenamine

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About This Item

실험식(Hill 표기법):
C18H13N
CAS Number:
Molecular Weight:
243.30
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

분석

95%

형태

solid

mp

209-211 °C (lit.)

SMILES string

Nc1cc2c3ccccc3ccc2c4ccccc14

InChI

1S/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2

InChI key

KIVUHCNVDWYUNP-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Produces tumors in mice.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

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1 of 2

B G Lake et al.
Toxicology and applied pharmacology, 138(2), 231-241 (1996-06-01)
Precision-cut liver slices were prepared from male Sprague-Dawley rats (pretreated with or without Aroclor 1254), male Dunkin-Hartley guinea pigs, male cynomolgus monkeys, and humans. Liver slices were cultured for 24 hr using a dynamic organ culture system in medium containing
H Yamazaki et al.
Carcinogenesis, 15(3), 465-470 (1994-03-01)
In order to address the hypothesis that 6-aminochrysene (6-AC) is converted to genotoxic products by cytochrome P450 enzymes via two activation pathways (N-hydroxylation and epoxidation), the activation of 6-AC and trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene (6-AC-diol) to genotoxic metabolites was examined in rat and
K B Delclos et al.
Carcinogenesis, 8(11), 1703-1709 (1987-11-01)
Since 6-nitrochrysene and 6-aminochrysene have shown activity in carcinogenicity bioassays, we have begun an investigation of their metabolic activation pathways and the nature of the carcinogen-DNA adducts that may be formed. N-Hydroxy-6-aminochrysene (N-hydroxy-AC), a candidate proximate or ultimate carcinogen and
K B Delclos et al.
IARC scientific publications, (124)(124), 79-86 (1993-01-01)
Carcinogenic arylamines and nitroaromatic hydrocarbons are chemicals that present occupational health hazards and share pathways of metabolic activation. The 32P-postlabelled DNA adducts formed in Chinese hamster ovary (CHO) cells treated with metabolites from two pathways that are common to the
M Mimura et al.
Drug metabolism and disposition: the biological fate of chemicals, 21(6), 1048-1056 (1993-11-01)
A cytochrome P-450 (P-450) enzyme of the CYP2B subfamily was partially purified from human liver microsomes and characterized with respect to immunochemical properties, N-terminal amino acid sequence, and catalytic activities toward typical P-450 substrates. P-450 enzymes were monitored in chromatographic

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