930660

Pomalidomide 4′-PEG₃-amine hydrochloride

≥95%

• 동의어(들): 1H-Isoindole-1,3(2H)-dione hydrochloride, 4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione hydrochloride, 4-[[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl) hydrochloride
• 실험식(Hill 표기법): C₂₁H₂₈N₄O₇ · xHCl
• CAS Number: 2446474-09-3
• Molecular Weight: 448.47 (free base basis)
• MDL number: MFCD32063491
• UNSPSC 코드: 12352116
• NACRES: NA.21

속성

• ligand: pomalidomide
• Quality Level: 100
• 분석: ≥95%
• 형태: powder
• 작용기: amine
• 저장 온도: 2-8°C
• SMILES string: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O

설명

애플리케이션

Pomalidomide 4′-PEG₃-amine Hydrochloride is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Allows rapid conjugation with carboxyl linkers due to the presence of an amine group via peptide coupling reactions. It is also active for linker attachment via reductive amination, and a basic building block for development of a protein degrader library.


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기타 정보

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법적 정보

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable