928321

BrettPhos Pd G3 ChemBeads

• 동의어(들): [(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate methanesulfonate
• 실험식(Hill 표기법): C₄₈H₆₆NO₅PPdS
• CAS Number: 1470372-59-8
• Molecular Weight: 906.50
• MDL number: MFCD22572666

속성

• 분석: ~5 wt.% loading of catalyst
• Quality Level: 100
• 형태: solid
• 반응 적합성: reagent type: catalyst; reaction type: Cross Couplings
• 라벨링 범위: ~5 wt. % loading of catalyst

설명

일반 설명

BrettPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. BrettPhos Pd G3 is an excellent reagent for Buchwald-Hartwig cross-coupling reaction. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

For larger scale uses, product also available in powdered form (761605)

애플리케이션

BrettPhos Pd G3 may be used for the C-N coupling reaction between monosubstituted ureas and 1,2 dihaloaromatic system to form benzimidazolones.It may be used in the synthesis of following compounds:

• [Pd(cinnamyl)(BrettPhos)]OTf by reacting with [(cinnamyl)PdCl]₂ and AgOTf.
• [Pd(crotyl)(BrettPhos)]OTf by reacting with [(crotyl)PdCl]₂ and AgOTf.
• [Pd(allyl)(BrettPhos)]OTf by reacting with [(allyl)PdCl]₂ and AgOTf.
• Pd(allyl)(BrettPhos)Cl by reacting with [(allyl)PdCl]₂.

Learn more about ChemBeads products

기타 정보

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안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H350i
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 1B Inhalation
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable