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Merck
모든 사진(2)

Key Documents

919012

Sigma-Aldrich

PEI Prime linear polyethylenimine

suitable for gene delivery

동의어(들):

PEI

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About This Item

Linear Formula:
(C2H5N . HCl)n
CAS Number:
MDL number:
UNSPSC 코드:
12162002
NACRES:
NA.23

Quality Level

형태

powder

색상

white to off-white

저장 온도

2-8°C

애플리케이션

PEI Prime is a cationic polymer designed for high-yield, reproducible and scalable drug and gene delivery. As a gene carrier, PEI forms a complex with nucleic acids via electrostatic self-assembly between the negatively charged nucleic acid phosphate groups and positively charged PEI amine groups. Due to this interaction, PEI has been extensively explored as a gene carrier and is one of the most effective synthetic polymers for the delivery of nucleic acids into cells through endocytosis.


PEI Prime uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.

법적 정보

PEI Prime is a trademark of Serochem LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

S M Zou et al.
The journal of gene medicine, 2(2), 128-134 (2000-05-16)
Several nonviral vectors including linear polyethylenimine (L-PEI) confer a pronounced lung tropism to plasmid DNA when injected into the mouse tail vein in a nonionic solution. and results We have optimized this route by injecting 50 microg DNA with excess

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