408719

Polyethylenimine, branched

average M_w ~800 by LS, average M_n ~600 by GPC

• 동의어(들): PEI, ethylenediamine branched
• Linear Formula: H(NHCH₂CH₂)_nNH₂
• CAS Number: 25987-06-8
• MDL number: MFCD00084427
• UNSPSC 코드: 12162002
• NACRES: NA.23

속성

• 형태: viscous liquid
• Quality Level: 200
• 분자량: average M_n ~600 by GPC; average M_w ~800 by LS
• refractive index: n20/D 1.5240
• density: 1.050 g/mL at 25 °C
• InChI: 1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2
• InChI key: SFLOAOINZSFFAE-UHFFFAOYSA-N

설명

일반 설명

Polyethyleneimine is a hydrophilic polymerwidely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids. Owing to its excellentphysicochemical properties, it is applied in many fields like the separationand purification of proteins, carbon dioxide absorption, drug carriers,effluent treatment, and biological labels.

애플리케이션

Branched PEI can be used as a precursor to synthesize conjugated polyplexes for efficient gene transfection. Conjugation of PEI with Jeffamine polyether and guanidinylation of the amino groups of PEI reduce the cytotoxicity of the polyplexes and protect them from aggregation in the presence of serum proteins.

Bamboo charcoal impregnated with PEI can be used as a CO₂ adsorbent. Numerous amino groups present in PEI can react with CO₂ due to acid-alkali interaction and enhance the adsorption capacity of bamboo charcoal.

It can also be used to prepare cross-linked water-soluble polymers with high coordination capabilities towards organic drug molecules.

특징 및 장점

• Branched PEI has better complexation and buffering capacity.
• High ion exchange capacity and affinity toward proteins.
• SignificantDNA transfer efficiency.

물리적 형태

Branched polymer

안전성 정보

• 픽토그램: GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H302,H318,H411
• 예방조치 성명서: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P391
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 356.0 °F
• Flash Point (°C): 180 °C
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter