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Merck
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Key Documents

918962

Sigma-Aldrich

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

PEG average Mn 5000, PDLA average Mn 50000

동의어(들):

Biodegradable, Block copolymer, Drug delivery, PEG-PLA, PLLA, mPEG-PLA, mPEG-PLLA

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About This Item

Linear Formula:
HO[CH(CH3)COO]m[CH2CH2O]nCH3
UNSPSC 코드:
12352106
NACRES:
NA.23

형태

solid

Quality Level

분자량

PDLA average Mn 50,000 (by NMR)
PDLA average Mn 50000
PEG average Mn 5,000 (by NMR)
PEG average Mn 5000

색상

white to yellow

저장 온도

2-8°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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문서 라이브러리 방문

Cynthia Griggins et al.
HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues, 23(1), 43-56 (2010-12-21)
This essay describes and critically evaluates a co-operative educational program to train Ugandan health care workers in bioethics. It describes one "bottom-up" effort, a week-long intensive workshop in bioethics provided by the authors to health care professionals in a developing
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

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