909858

Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide)

PEG average M_n 5,000, PLGA average M_n 20,000, lactide:glycolide 50:50

• 동의어(들): COOH-PEG-PLGA, Carboxylic acid PEG-PLGA
• Linear Formula: H[(C₃H₄O₂)_x(C₂H₂O₂)_y]_mO[C₂H₄O]_nC₂H₃O₂
• UNSPSC 코드: 12352106
• NACRES: NA.23

속성

• 형태: powder or chunks
• 피드(feed) 비율: lactide:glycolide 50:50
• 분자량: PEG average M_n 5,000 (by NMR); PLGA average M_n 20,000 (by NMR)
• 색상: white to tan
• 저장 온도: −20°C

설명

애플리케이션

Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable