907197

1,4-Dinitro-1-imidazole

• 동의어(들): 1,4-DNIm, 1,4-Dinitroimidazole, Bifunctional bioconjugation reagent
• 실험식(Hill 표기법): C₃H₂N₄O₄
• CAS Number: 19182-81-1
• Molecular Weight: 158.07
• MDL number: MFCD00297235
• UNSPSC 코드: 12352005

속성

• 분석: ≥95%
• 양식: solid
• 저장 온도: −20°C
• InChI: 1S/C3H2N4O4/c8-6(9)3-1-5(2-4-3)7(10)11/h1-2H
• InChI key: HZPSREFSUPXCMN-UHFFFAOYSA-N

설명

애플리케이션

1,4-Dinitro-1-imidazole (1,4-DNIm) and other dinitroimidazoles were demonstrated to be bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. In acidic to neutral aqueous conditions, 1,4-DNIms chemoselectively react with cysteines; in organic solvents in the presence of base, 1,4-DNIms chemoselectively react with lysines to form stable conjugates

기타 정보

Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable