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Merck
모든 사진(1)

Key Documents

906433

Sigma-Aldrich

TLAM-Iδ1LVproR-U-13C Methyl Labeling Kit

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모든 사진(1)

About This Item

UNSPSC 코드:
12352200
NACRES:
NA.12

기술

bio NMR: suitable

Quality Level

200

배송 상태

dry ice

저장 온도

−70°C

일반 설명

TLAM-Iδ1LVproR-U-[13C] kit has 13C isotopomer precursors and contains protocol instructions for creation of isotopically-labeled proteins.

애플리케이션

For protein methyl group assignment by 13C isotope labeling of amino acid methyl groups separately or simultaneously.
TLAM-Iδ1LVproR-U-[13C] kit is used to label isoleucine, leucine and valine residues with 13C isotopomer. This kit has been tested with protein isotopic labeling in E. coli. It can be used to increase the sensitivity, interaction correlation and resolution of larger proteins in NMR spectroscopy (typically above 50 KDa).

포장

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

픽토그램

Corrosion
GHS05

신호어

Danger

유해 및 위험 성명서

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

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시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Rime Kerfah et al.
Journal of biomolecular NMR, 63(4), 389-402 (2015-11-15)
A new strategy for the NMR assignment of aliphatic side-chains in large perdeuterated proteins is proposed. It involves an alternative isotopic labeling protocol, the use of an out-and-back (13)C-(13)C TOCSY experiment ((H)C-TOCSY-C-TOCSY-(C)H) and an optimized non-uniform sampling protocol. It has
Rime Kerfah et al.
Current opinion in structural biology, 32, 113-122 (2015-04-17)
Nuclear magnetic resonance (NMR) spectroscopy is a uniquely powerful tool for studying the structure, dynamics and interactions of biomolecules at atomic resolution. In the past 15 years, the development of new isotopic labeling strategies has opened the possibility of exploiting
Silke Wiesner et al.
Current opinion in structural biology, 35, 60-67 (2015-09-26)
Intermolecular interactions are indispensible for biological function. Here we discuss how novel NMR techniques can provide unique insights into the assembly, dynamics and regulation of biomolecular complexes. We focus on applications that exploit the methyl TROSY effect and show that

문서

Methyl Isotope-Labeling of Proteins from NMR-Bio

Methyl groups are ideal probes for studying protein structure and function by NMR. Choose among user-friendly kits for isotope labeling of a single type or multiple types of methyl groups.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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