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Merck
모든 사진(1)

Key Documents

900393

Sigma-Aldrich

Folate-PEG2000-COOH

average Mn 2,000

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About This Item

Linear Formula:
C19H19N8O5(C2H4O)nC2H3O2
UNSPSC 코드:
51171641
NACRES:
NA.23

형태

powder

Quality Level

분자량

average Mn 2,000

전이 온도

Tm 39-49 °C

저장 온도

−20°C

애플리케이션

The folate end group may be used for target-specific cellular uptake of drug delivery vehicles and the carboxylate group can be used for further conjugation to make drug conjugates, polymeric nanoparticles, or folate targeting liposomes.

법적 정보

Product of JenKem Technology.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

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Biomaterials, 34(20), 4849-4859 (2013-04-02)
A nanocarrier delivery system that can simultaneously deliver a chemotherapeutic drug and siRNA to the tumor is emerging as a promising treatment strategy for cancer treatment. In this study, a multifunctional PHD/PPF/siRNA complexes was developed by one-step assembly of prefunctionalized
Dipanjan Pan et al.
Chemical communications (Cambridge, England), (19)(19), 2400-2401 (2003-11-01)
Shell cross-linked nanoparticles (SCKs) constitute a unique class of materials with amphiphilic core-shell morphology; SCKs are characterised by their structural integrity and available functionality to attach receptor-recognising or receptor-specific ligands on the shell surface and, therefore, hold great potential in
Hyuk Sang Yoo et al.
Journal of controlled release : official journal of the Controlled Release Society, 100(2), 247-256 (2004-11-17)
For folate-receptor-targeted anti-cancer therapy, doxorubicin aggregates in a nano-scale size were produced employing doxorubicin-polyethylene glycol-folate (DOX-PEG-FOL) conjugate. Doxorubicin and folate were respectively conjugated to alpha- and omega-terminal end group of a PEG chain. The conjugates assisted to form doxorubicin nano-aggregates
Sun Hwa Kim et al.
Langmuir : the ACS journal of surfaces and colloids, 21(19), 8852-8857 (2005-09-07)
Poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles with anionic surface charge were surface coated with cationic di-block copolymer, poly(L-lysine)-poly(ethylene glycol)-folate (PLL-PEG-FOL) conjugate, for enhancing their site-specific intracellular delivery against folate receptor overexpressing cancer cells. The PLGA nanoparticles coated with the conjugate were characterized

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