추천 제품
material
PEG 5000
양식
dispersion in H2O
nanoparticles
포장
poly bottle of 1 mL
OD
50
직경
20 nm
pH
6.0-8.0 (25 °C)
solubility
water: miscible
density
1.00 g/cm3
λmax
520 nm
작용기
carboxylic acid
저장 온도
2-8°C
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일반 설명
Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.
애플리케이션
Carboxylic acid functionalized, PEG 5000 coated, OD 50, and H2O dispersed gold nanoparticles can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
The carboxylic acid group binds with various proteins and can be used in targeted drug delivery and gene therapy.
특징 및 장점
Decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. The PEG increases the stability of the nanoparticles and prevents agglomeration.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)
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