764191

Alkyne-PEG5-N-hydroxysuccinimidyl ester

• 동의어(들): Acetylene-PEG5-NHS ester, Alkyne-PEG5-NHS ester, Alkyne-PEG5-succinimidyl ester
• 실험식(Hill 표기법): C₁₈H₂₇NO₉
• Molecular Weight: 401.41
• MDL number: MFCD22574798
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329767105
• NACRES: NA.22

속성

• 형태: liquid
• Quality Level: 100
• 반응 적합성: reaction type: click chemistry; reagent type: cross-linking reagent
• 작용기: NHS ester; alkyne
• 저장 온도: −20°C
• SMILES string: C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
• InChI: 1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2
• InChI key: ACZDUKRWTPZVRP-UHFFFAOYSA-N

설명

애플리케이션

Heterobifunctional crosslinker enabling the connection of an azide containing compound or biomolecule to one with a primary amine. The succinimidyl ester group will react preferentially with primary amines to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification amine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable