566357

m-Toluenesulfonyl chloride

97%

• 동의어(들): 3-Methylbenzenesulfonyl chloride
• Linear Formula: CH₃C₆H₄SO₂Cl
• CAS Number: 1899-93-0
• Molecular Weight: 190.65
• MDL number: MFCD00051747
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24880292
• NACRES: NA.22

속성

• 분석: 97%
• refractive index: n20/D 1.5490 (lit.)
• bp: 252-253 °C (lit.)
• density: 1.314 g/mL at 25 °C (lit.)
• SMILES string: Cc1cccc(c1)S(Cl)(=O)=O
• InChI: 1S/C7H7ClO2S/c1-6-3-2-4-7(5-6)11(8,9)10/h2-5H,1H3
• InChI key: KFPMLWUKHQMEBU-UHFFFAOYSA-N

설명

일반 설명

m-Toluenesulfonyl chloride can be synthesized via chlorination of m-thiocresol in glacial acetic acid.

애플리케이션

m-Toluenesulfonyl chloride may be used in the synthesis of mesityl-m-tolyl sulfone via reaction with mesitylene.

Reactant involved in they synthesis of biologically active molecules including:

• Small molecule ligands for the Stat3 SH2 domain
• Isoindoline-5-propenehydroxamates for use as histone deactylase inhibitors
• Phenyl-pyrazolylamine-based derivatives as FLT3 kinase inhibitors
• Aryldisulfonamides with antibacterial activity
• Quinazoline analogs for the treatment of Gaucher disease
• 17β-HSD2 inhibitors for the treatment of osteoporosis

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): 225.0 °F - closed cup
• Flash Point (°C): 107.2 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter