460923

Propargyl chloroformate

96%

• 동의어(들): (Prop-2-ynyloxy)carbonyl chloride, 2-Propyn-1-yl carbonochloridate, 2-Propynyl chloroformate, Prop-2-yn-1-yl carbonochloridate, Propargyloxycarbonyl chloride
• Linear Formula: HC≡CCH₂OCOCl
• CAS Number: 35718-08-2
• Molecular Weight: 118.52
• Beilstein: 1745399
• MDL number: MFCD00270127
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24869771
• NACRES: NA.22

속성

• vapor pressure: 0.65 psi ( 20 °C)
• Quality Level: 100
• 분석: 96%
• 반응 적합성: reaction type: click chemistry
• refractive index: n20/D 1.435 (lit.)
• bp: 118-122 °C (lit.)
• density: 1.215 g/mL at 25 °C (lit.)
• 작용기: chloro
• 저장 온도: 2-8°C
• SMILES string: ClC(=O)OCC#C
• InChI: 1S/C4H3ClO2/c1-2-3-7-4(5)6/h1H,3H2
• InChI key: RAMTXCRMKBFPRG-UHFFFAOYSA-N

설명

일반 설명

Propargyl chloroformate is a propargyl ester. It serves as a protecting group for the hydroxy and amino functional group. Rates of solvolysis of propargyl chloroformate has been analyzed in various solvents of widely varying nucleophilicity and ionizing power values using the extended Grunwald-Winstein equation.

애플리케이션

Propargyl chloroformate may be used for the preparation of the following:

• binaphthol-diacetylene derivatives
• propargyl pentafluorophenyl carbonate
• N-Poc protected amino acids (Poc = propargyloxycarbonyl)

안전성 정보

• 픽토그램: GHS02,GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H226,H302,H311 + H331,H314
• 예방조치 성명서: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 86.0 °F - closed cup
• Flash Point (°C): 30 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter