445088

mono-Ethyl malonate

• 동의어(들): (Ethoxycarbonyl)acetic acid, 3-Ethoxy-3-oxopropanoic acid, Ethyl hydrogen malonate, Ethyl malonate, Monoethyl hydrogen malonate
• Linear Formula: HO₂CCH₂CO₂C₂H₅
• CAS Number: 1071-46-1
• Molecular Weight: 132.11
• EC Number: 213-992-7
• MDL number: MFCD00020490
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24868159
• NACRES: NA.22

속성

• 양식: liquid
• 불순물: <10% ethyl malonate, potassium salt
• refractive index: n20/D 1.435 (lit.)
• bp: 106.5 °C/3 mmHg (lit.)
• density: 1.119 g/mL at 25 °C (lit.)
• 작용기: carboxylic acid; ester
• SMILES string: CCOC(=O)CC(O)=O
• InChI: 1S/C5H8O4/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3,(H,6,7)
• InChI key: HGINADPHJQTSKN-UHFFFAOYSA-N

설명

애플리케이션

Reactant for:

• Preparation of tetramic acids via Dieckmann ring closure
• Organocatalytic decarboxylative Doebner-Knoevenagel reactions
• Conjugation to amino-modified oligonucleotides
• Acylation reactions (acylation agent)
• Indole glyoxylamides for potential Prion disease treatment
• Knoevenagel condensation with aldehydes

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 235.4 °F - closed cup
• Flash Point (°C): 113 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter