콘텐츠로 건너뛰기
Merck
모든 사진(2)

주요 문서

375462

Sigma-Aldrich

3H-1,2-Benzodithiol-3-one

97%

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C7H4OS2
CAS Number:
Molecular Weight:
168.24
Beilstein:
119513
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

형태

solid

mp

74-77 °C (lit.)

solubility

toluene: soluble 2.5%, clear, yellow

작용기

disulfide

SMILES string

O=C1SSc2ccccc12

InChI

1S/C7H4OS2/c8-7-5-3-1-2-4-6(5)9-10-7/h1-4H

InChI key

GZTYTTPPCAXUHB-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

3H-1,2-Benzodithiol-3-one is a heterocyclic building block.
3H-1,2-Benzodithiol-3-one is reported to react with triphenylphosphine to afford dithiosalicylide.

애플리케이션

3H-1,2-Benzodithiol-3-one (1,2-benzodithiol-3-one) may be used as sulfur-transferring agent for the transformation of H-phosphonothioate and H-phosphonate diesters into the corresponding phosphorodi- and phosphoromonothioates.
3H-1,2-Benzodithiol-3-one may be employed as sulfurizing reagent in the preparation of phosphorothioate-containing oligodeoxyribonucleotides.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Q Xu et al.
Nucleic acids research, 24(9), 1602-1607 (1996-05-01)
Previous methods for the preparation of phosphorothioate-containing oligodeoxyribonucleotides rely on the reaction of phosphite triesters with sulfurizing reagents such as tetraethylthiuram disulfide (TETD) and 3H-1,2-benzodithiol-3-one 1,1-dioxide (Beaucage reagent). However, these and other sulfurizing reagents suffer from several disadvantages, and there
Nucleoside H-phosphonates. 13. Studies on 3H-1, 2-benzodithiol-3-one derivatives as sulfurizing reagents for H-phosphonate and H-phosphonothioate diesters.
Stawinski J and Thelin M.
The Journal of Organic Chemistry, 56(17), 5169-5175 (1991)
Novel syntheses of dithiosalicylide.
Mitra K and Gates KS.
Tetrahedron Letters, 36(9), 1391-1394 (1995)
Santhosh Sivaramakrishnan et al.
Bioorganic & medicinal chemistry letters, 18(10), 3076-3080 (2007-12-11)
Though less potent than the parent natural product leinamycin, S-deoxyleinamycin displays activity against human cancer cell lines that is comparable to many clinically used agents. The results reported here suggest that the 1,2-dithiolan-3-one heterocycle found in S-deoxyleinamycin reacts with thiols

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.