364517
L-Tryptophan methyl ester hydrochloride
98%, for peptide synthesis
동의어(들):
(S)-Tryptophan methyl ester hydrochloride, H-(L)-Trp-OMe hydrochloride, L-(-)-Tryptophan methyl ester hydrochloride, Tryptophan methyl ester hydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C12H14N2O2 · HCl
CAS Number:
Molecular Weight:
254.71
Beilstein:
4240280
EC Number:
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
추천 제품
제품명
L-Tryptophan methyl ester hydrochloride, 98%
Quality Level
분석
98%
광학 활성
[α]20/D +18°, c = 5 in methanol
반응 적합성
reaction type: solution phase peptide synthesis
mp
218-220 °C (lit.)
응용 분야
peptide synthesis
SMILES string
Cl.COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12
InChI
1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H/t10-;/m0./s1
InChI key
XNFNGGQRDXFYMM-PPHPATTJSA-N
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애플리케이션
L-Tryptophan methyl ester hydrochloride can be used as a reactant to prepare:
- Oxamoyl derivatives of N-(2-aminobenzoyl)-L-tryptophan (dipeptides) by acylation reaction with 3,1-benzoxazinones.
- Tadalafil (Cialis), a type-V phosphodiesterase (PDE5) inhibitor.
- Isoroquefortine C.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Christine Böttcher et al.
Journal of experimental botany, 62(12), 4267-4280 (2011-05-06)
Nine Gretchen Hagen (GH3) genes were identified in grapevine (Vitis vinifera L.) and six of these were predicted on the basis of protein sequence similarity to act as indole-3-acetic acid (IAA)-amido synthetases. The activity of these enzymes is thought to
Takeshi Miyazaki et al.
Journal of neurosurgery, 111(2), 230-237 (2009-02-10)
Indoleamine 2,3-dioxygenase (IDO), a kynurenine pathway (KP) enzyme catalyzing oxidation of the essential amino acid tryptophan (Trp), is thought to be involved in the immune resistance of malignant tumors through T-cell inactivation caused by Trp depletion and metabolite accumulation. Human
Haruki Nishizawa et al.
The journal of obstetrics and gynaecology research, 34(1), 1-6 (2008-01-30)
We have previously demonstrated that mRNA expression and enzyme activity levels of placental indoleamine 2,3-dioxygenase (IDO), which degrades L-tryptophan and blocks the proliferation of T cells, are significantly low in patients with severe pre-eclampsia. From this observation, we hypothesized that
Y Sakai et al.
Neurology, 70(6), 431-439 (2008-02-06)
Altered serotonin (5-HT) neurotransmission has been implicated in the pathophysiology of migraine headache. To test this hypothesis in migraine patients in vivo using PET and alpha-[(11)C]methyl-l-tryptophan as a surrogate marker of brain 5-HT synthetic rate during different phases of their
Michael Behen et al.
Movement disorders : official journal of the Movement Disorder Society, 22(15), 2256-2262 (2007-08-22)
Symptoms in Tourette syndrome (TS) are likely related to abnormalities involving multiple neurotransmitter systems in striatal-thalamo-cortical circuitry. Although prior studies have found abnormal levels of tryptophan, serotonin, and their metabolites in blood, cerebrospinal fluid and brain tissue of TS patients
Chromatograms
application for HPLC자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.