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Merck
모든 사진(1)

주요 문서

228818

Sigma-Aldrich

Diethyl propylmalonate

99%

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About This Item

Linear Formula:
CH3CH2CH2CH(COOC2H5)2
CAS Number:
Molecular Weight:
202.25
Beilstein:
510157
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

99%

형태

liquid

refractive index

n20/D 1.418 (lit.)

bp

221-222 °C (lit.)

density

0.987 g/mL at 25 °C (lit.)

SMILES string

CCCC(C(=O)OCC)C(=O)OCC

InChI

1S/C10H18O4/c1-4-7-8(9(11)13-5-2)10(12)14-6-3/h8H,4-7H2,1-3H3

InChI key

GRRSDGHTSMJICM-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Diethyl propylmalonate was used in the synthesis of propylacrylic acid (PAA).

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

197.6 °F - closed cup

Flash Point (°C)

92 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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문서 라이브러리 방문

Mohamed E H El-Sayed et al.
Journal of controlled release : official journal of the Controlled Release Society, 104(2), 417-427 (2005-06-29)
Limited cytoplasmic delivery of enzyme-susceptible drugs remains a significant challenge facing the development of protein and nucleic acid therapies that act in intracellular compartments. "Smart" pH-responsive, membrane-destabilizing polymers present a new approach to shuttling therapeutic molecules past the endosomal membrane
Kyle M Hocking et al.
Tissue engineering. Part A, 25(5-6), 416-426 (2018-08-23)
Subarachnoid hemorrhage (SAH) is associated with vasospasm that is refractory to traditional vasodilators, and inhibition of vasospasm after SAH remains a large unmet clinical need. SAH causes changes in the phosphorylation state of the small heat shock proteins (HSPs), HSP20
Feng Qiu et al.
Biomaterials, 182, 82-91 (2018-08-15)
Cancer vaccines targeting patient-specific tumor neoantigens have recently emerged as a promising component of the rapidly expanding immunotherapeutic armamentarium. However, neoantigenic peptides typically elicit weak CD8+ T cell responses, and so there is a need for universally applicable vaccine delivery
Brian C Evans et al.
ACS nano, 9(6), 5893-5907 (2015-05-26)
A platform technology has been developed and tested for delivery of intracellular-acting peptides through electrostatically complexed nanoparticles, or nano-polyplexes, formulated from an anionic endosomolytic polymer and cationic therapeutic peptides. This delivery platform has been initially tested and optimized for delivery
Xi Zhan et al.
Pharmaceutical research, 32(7), 2280-2291 (2015-01-17)
A key step of delivering extracellular agents to its intracellular target is to escape from endosomal/lysosomal compartments, while minimizing the release of digestive enzymes that may compromise cellular functions. In this study, we examined the intracellular distribution of both fluorecent

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