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Merck
모든 사진(1)

주요 문서

219630

Sigma-Aldrich

DL-2,3-Diaminopropionic acid monohydrochloride

98%

동의어(들):

3-Amino-DL-alanine monohydrochloride

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About This Item

Linear Formula:
NH2CH2CH(NH2)COOH · HCl
CAS Number:
Molecular Weight:
140.57
Beilstein:
5293359
EC Number:
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.22

분석

98%

양식

solid

반응 적합성

reaction type: solution phase peptide synthesis

mp

232 °C (dec.) (lit.)

응용 분야

peptide synthesis

SMILES string

Cl[H].NCC(N)C(O)=O

InChI

1S/C3H8N2O2.ClH/c4-1-2(5)3(6)7;/h2H,1,4-5H2,(H,6,7);1H

InChI key

SKWCZPYWFRTSDD-UHFFFAOYSA-N

일반 설명

DL-2,3-Diaminopropionic acid monohydrochloride also known as 3-Amino-DL-alanine monohydrochloride, is commonly used in solution phase peptide synthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

J N Kalyani et al.
Journal of bacteriology, 194(20), 5604-5612 (2012-08-21)
Diaminopropionate ammonia lyase (DAPAL) is a pyridoxal-5'phosphate (PLP)-dependent enzyme that catalyzes the conversion of diaminopropionate (DAP) to pyruvate and ammonia and plays an important role in cell metabolism. We have investigated the role of the ygeX gene of Escherichia coli
Changming Zhao et al.
FEBS letters, 582(20), 3125-3131 (2008-08-12)
Zwittermicin A (ZwA) is a hybrid polyketide-non-ribosomal peptide that is thought to be biosynthesized from five proposed building blocks, including the 2,3-diaminopropionate. Candidate genes for de novo biosynthesis of 2,3-diaminopropionate, zwa5A and zwa5B, have been identified in a previous study.
Meredith W Miller et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 719-724 (2009-01-15)
There is a grave need for safer antiplatelet therapeutics to prevent heart attack and stroke. Agents targeting the interaction of platelets with the diseased vessel wall could impact vascular disease with minimal effects on normal hemostasis. We targeted integrin alpha(2)beta(1)
Joana R Viola et al.
Bioorganic & medicinal chemistry letters, 22(17), 5635-5638 (2012-08-04)
Here we report a novel class of peptides-d-diaminopropionic acids (Dap)-for gene delivery. These peptides have attractive properties for gene delivery, and the advantage that they can be easily manipulated in relation to their composition, abiding with tailored-design. We characterized the
Giovanni N Roviello et al.
Amino acids, 43(6), 2537-2543 (2012-06-13)
In this work, we report a synthetic approach to a Fmoc-protected nucleoamino acid, based on L-diaminopropanoic acid, carrying the DNA nucleobase on the alpha-amino group by means of an amide bond, suitable for the solid-phase synthesis of novel nucleopeptides of

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