202371

Poly(ethylene glycol)

average M_n 300, hydroxyl

• 동의어(들): Polyethylene glycol, PEG
• Linear Formula: H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• MDL number: MFCD00081839
• UNSPSC 코드: 12352104
• PubChem Substance ID: 24852059
• NACRES: NA.23

속성

• product name: Poly(ethylene glycol), average M_n 300
• 형태: viscous liquid
• Quality Level: 200
• 분자량: M_n 285-315; average M_n 300
• refractive index: n20/D 1.463
• pH: 6-7 (23 °C, at 10 g/l)
• 점도: 5.8 cSt(210 °F)(lit.)
• mp: −15-−8 °C (lit.)
• density: 1.125 g/mL at 25 °C
• Mw/Mn: 1.1 (typical)
• Ω-끝: hydroxyl
• α-끝: hydroxyl
• SMILES string: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

설명

일반 설명

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks, PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

애플리케이션

• PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.: This study demonstrates that polyethylene glycol (PEG) modification significantly enhances the thermostability and inhibitor resistance of Bst DNA polymerase, highlighting PEG′s potential in improving enzyme performance for biotechnological applications (Yang et al., 2024).


• Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: The incorporation of PEG in the lyophilization process of a cell-free protein expression system demonstrates its role in enhancing the stability and efficiency of biotechnological workflows (Alfaro-Palma et al., 2024).


• A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer.: This review highlights the application of PEGylated nanomaterials in photodynamic therapy, emphasizing its significance in improving biocompatibility and therapeutic efficacy in cancer treatments (Singh et al., 2024).

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 428.0 °F - closed cup
• Flash Point (°C): 220.00 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves