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Merck
모든 사진(2)

Key Documents

191213

Sigma-Aldrich

5-Aminoorotic acid

99%

동의어(들):

5-Amino-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid, 5-Amino-6-carboxy-2,4-dihydroxypyrimidine

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About This Item

실험식(Hill 표기법):
C5H5N3O4
CAS Number:
Molecular Weight:
171.11
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

99%

형태

solid

mp

>300 °C (lit.)

작용기

carboxylic acid

SMILES string

NC1=C(NC(=O)NC1=O)C(O)=O

InChI

1S/C5H5N3O4/c6-1-2(4(10)11)7-5(12)8-3(1)9/h6H2,(H,10,11)(H2,7,8,9,12)

InChI key

HWCXJKLFOSBVLH-UHFFFAOYSA-N

일반 설명

5-Aminoorotic acid forms complexes with cerium (III), lanthanum (III) and neodymium (III). It reacts with dianhydride of ethylenedinitrilotetraacetic acid in dry DMF or DMSO to yield functionalized dicarboxamide derivatives.

애플리케이션

5-Aminoorotic acid was used as an internal standard during the electrochemical determination of orotic acid.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

Irena Kostova et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 4(4), 371-378 (2008-08-05)
The cerium (III), lanthanum (III) and neodymium (III) complexes of 5-aminoorotic acid were synthesized and their structures were determined by means of theoretical study, spectral and physicochemical analysis. Significant differences in the spectra of the complexes were observed as compared
Synthesis and characterisation of chelating polycarboxylate ligands capable of forming intermolecular, complementary triple hydrogen bonds.
Georgopoulou AS, et al.
J. Chem. Soc., Dalton Trans., 11, 1869-1878 (1998)
Tommaso R I Cataldi et al.
Journal of chromatography. A, 1107(1-2), 130-138 (2006-01-13)
The application of activated pulsed amperometric detection (APAD) for the determination of orotic acid (OrA) in real samples at a gold working electrode in alkaline solutions, in combination with anion-exchange chromatography, is reported. Such an activated potential waveform was designed
Rony Panarsky et al.
Cancer & metabolism, 8, 7-7 (2020-08-11)
The loss-of-function mutation of fumarate hydratase (FH) is a driver of hereditary leiomyomatosis and renal cell carcinoma (HLRCC). Fumarate accumulation results in activation of stress-related mechanisms leading to upregulation of cell survival-related genes. To better understand how cells compensate for

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