SNCA
synuclein, alpha (non A4 component of amyloid precursor)
동의어:
NACP, PARK1, PARK4, PD1
종:
Human SNCA (6622), Mouse Snca (20617), Rat Snca (29219), chicken SNCA (395393), Horse SNCA (100053270), domestic cat SNCA (101091694), dog SNCA (478478), cow SNCA (282857), sheep SNCA (100294604), domestic guinea pig Snca (100725375)
UniProtKB ID:
Clone ID:
- Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
- Mouse(20617) synuclein, alpha
- Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
- chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
- Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
- domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
- dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
- cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
- sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
- domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)
- naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
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Antibodies
Product Number
설명
종별 반응성
응용분야
Anti-phospho-α-Synuclein (Ser129) Antibody, clone 81A, clone 81A, from mouse,
종별 반응성
human, mouse
응용분야
electron microscopy
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-Synuclein-α (pTyr136) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
western blot
Anti-phospho-SNCA (pTyr125) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
western blot
western blot
Anti-phospho-SNCA (pSer129) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-α-Synuclein Antibody, clone Syn211 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
설명
종
α-Synuclein A53T human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
종
human
α-Synuclein human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
종
human