PYCARD
PYD and CARD domain containing
동의어:
ASC, CARD5, TMS, TMS-1, TMS1
종:
Human PYCARD (29108), Mouse Pycard (66824), Rat Pycard (282817), Zebrafish pycard (57923), dog PYCARD (489925), domestic cat PYCARD (101088449), cow PYCARD (282846), sheep PYCARD (101105208), Goat PYCARD (100861338), domestic guinea pig Pycard (100734858)
UniProtKB ID:
Clone ID:
- Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(66824) PYD and CARD domain containing
- Rat(282817) PYD and CARD domain containing
- Zebrafish(57923) PYD and CARD domain containing
- dog(489925) PYD and CARD domain containing
- domestic cat(101088449) PYD and CARD domain containing
- cow(282846) PYD and CARD domain containing
- sheep(101105208) PYD and CARD domain containing
- Goat(100861338) PYD and CARD domain containing
- domestic guinea pig(100734858) PYD and CARD domain containing
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-PYCARD, (N-terminal) antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-ASC/PYCARD Antibody, clone 1C19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot
western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ASC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
esiRNA
제품 번호
설명
종