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Merck

GABRA1

gamma-aminobutyric acid (GABA) A receptor, alpha 1

동의어:
ECA4, EJM, EJM5
:
UniProtKB ID:
Clone ID:
  • Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
  • Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
  • domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1

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Small Molecule - Agonist

제품 번호
설명
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
human
Piperidine-4-sulfonic acid, ,
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
human
Isoguvacine hydrochloride, solid,
human
γ-Aminobutyric acid, ≥99%,
human, rat

Small Molecule - Allosteric Modulator

제품 번호
설명
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
human
trans-Dehydroandrosterone, ≥99%,
human, rat
Etomidate, >98% (HPLC), powder,
human
Etomidate, European Pharmacopoeia (EP) Reference Standard,
human

Small Molecule - Antagonist

제품 번호
설명
Norfloxacin, analytical standard, ≥98% (TLC),
rat, human
Ofloxacin, fluoroquinolone antibiotic,
rat, human
Ciprofloxacin, ≥98% (HPLC),
rat, human
Etiocholan-3α-ol-17-one, ,
human, rat
Ro 15-4513, solid,
rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-GABA A Receptor α1 chain Antibody, NT, clone BD24, clone BD24, Chemicon®, from mouse,
종별 반응성
avian, bovine, human, pig
응용분야
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-GABRA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
western blot
Anti-GABA antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
drosophila, rat, wide range
응용분야
dot blot
immunohistochemistry
Anti-GABRA1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, human, rabbit
응용분야
western blot
Anti-GABA A Receptor β2/3 Antibody, clone 62-3G1, Upstate®, from mouse,
종별 반응성
bovine, human, rat
응용분야
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

제품 번호
설명
1,3-Diisopropylbenzene, 96%,
human
2-Isopropylphenol, 98%,
human
2,6-Xylenol, ≥99%, FG,
human
2-Isopropylphenol, ≥98%, FG,
human
Amentoflavone, ≥98.0% (HPLC),
human

Small Molecule - Ligand

제품 번호
설명
Ethyl alcohol, Pure, 200 proof, for molecular biology,
human
Etomidate, >98% (HPLC), powder,
human
Flumazenil, >99% (HPLC), solid,
rat, human
Carbamazepine, powder,
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
human

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
2,6-Dimethoxyphenol, 99%,
human
2-Hydroxy-3-isopropylbenzoic acid, 98%,
human
2,6-Dimethoxyphenol, natural, ≥96%,
human
Phenol solution, 5000 μg/mL in methanol, certified reference material,
human
Phenol solution, certified reference material, 500 μg/mL in methanol,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human GABRA1,
human
MISSION® esiRNA, targeting mouse Gabra1,
mouse