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Merck

ESR2

estrogen receptor 2 (ER beta)

동의어:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
:
UniProtKB ID:
Clone ID:
  • Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13983) estrogen receptor 2 (beta)
  • Rat(25149) estrogen receptor 2 (ER beta)
  • chicken(395575) estrogen receptor 2 (ER beta)
  • dog(403639) estrogen receptor 2 (ER beta)
  • Horse(100033964) estrogen receptor 2 (ER beta)
  • cow(281146) estrogen receptor 2 (ER beta)
  • domestic cat(101086317) estrogen receptor 2 (ER beta)
  • domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
  • Goat(100860823) estrogen receptor 2 (ER beta)
  • Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
  • sheep(443066) estrogen receptor 2 (ER beta)

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Small Molecule - Activator

제품 번호
설명
β-Nicotinamide adenine dinucleotide sodium salt, ,
human
β-Nicotinamide adenine dinucleotide, pkg of 10 mg (per vial),
human
β-Nicotinamide adenine dinucleotide hydrate, ≥95% (HPLC),
human
β-Nicotinamide adenine dinucleotide lithium salt from Saccharomyces cerevisiae, ≥95%,
human
β-Nicotinamide adenine dinucleotide hydrate, suitable for cell culture, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
human

Small Molecule - Agonist

제품 번호
설명
ERB-041, ≥98% (HPLC),
human
Estrone, ≥99%,
human, mouse, rat

Small Molecule - Allosteric Modulator

제품 번호
설명
Raloxifene hydrochloride, solid,
human
Estramustine sodium phosphate, ,
human
Raloxifene hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human
Raloxifene hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human

Small Molecule - Antagonist

제품 번호
설명
Fulvestrant, European Pharmacopoeia (EP) Reference Standard,
human
Fulvestrant for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Fulvestrant, >98% (HPLC),
human
Fulvestrant, United States Pharmacopeia (USP) Reference Standard,
human
2-Methoxyestradiol, powder,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Estrogen Receptor β Antibody, clone 9.88, clone 9.88, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunoprecipitation (IP)
western blot
Anti-phospho-Estrogen Receptor-β (pSer105) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Monoclonal Anti-ESR2 antibody produced in mouse, ,
종별 반응성
human, monkey, mouse
응용분야
ChIP
dot blot

flow cytometry

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-Estrogen Receptor-β antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

western blot
Anti-phospho-Estrogen Receptor-? (pSer87) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
α-Estradiol, powder, ≥98% (TLC),
human, rat
Estradiol, meets USP testing specifications,
human, mouse, rat
β-Estradiol, analytical standard,
human, mouse, rat
β-Estradiol, BioReagent, powder, suitable for cell culture,
human, mouse, rat
β-Estradiol, powder, γ-irradiated, suitable for cell culture,
human, mouse, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human ESR2,
human