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Merck

ESR2

estrogen receptor 2 (ER beta)

동의어:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
종:
Human ESR2 (2100), Mouse Esr2 (13983), Rat Esr2 (25149), chicken ESR2 (395575), dog ESR2 (403639), Horse ESR2 (100033964), cow ESR2 (281146), domestic cat ESR2 (101086317), domestic guinea pig Esr2 (100731304), Goat ESR2 (100860823) ...더
UniProtKB ID:
Q92731, A8K8K5, O60608, O60685, O60702, O60703, O75583, O75584
Clone ID:
  • Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13983) estrogen receptor 2 (beta)
  • Rat(25149) estrogen receptor 2 (ER beta)
  • chicken(395575) estrogen receptor 2 (ER beta)
  • dog(403639) estrogen receptor 2 (ER beta)
  • Horse(100033964) estrogen receptor 2 (ER beta)
  • cow(281146) estrogen receptor 2 (ER beta)
  • domestic cat(101086317) estrogen receptor 2 (ER beta)
  • domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
  • Goat(100860823) estrogen receptor 2 (ER beta)
  • Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
  • sheep(443066) estrogen receptor 2 (ER beta)

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Small Molecule - Activator

Product Number
설명
종
N0632
β-Nicotinamide adenine dinucleotide sodium salt, ,
종
human
N8535
β-Nicotinamide adenine dinucleotide, pkg of 50 mg (per vial),
종
human
N8285
β-Nicotinamide adenine dinucleotide, pkg of 10 mg (per vial),
종
human
43410
β-Nicotinamide adenine dinucleotide hydrate, ≥95% (HPLC),
종
human
N7132
β-Nicotinamide adenine dinucleotide lithium salt from Saccharomyces cerevisiae, ≥95%,
종
human

Small Molecule - Agonist

Product Number
설명
종
PZ0183
ERB-041, ≥98% (HPLC),
종
human
E9750
Estrone, ≥99%,
종
human, mouse, rat

Small Molecule - Allosteric Modulator

Product Number
설명
종
PHR1852
Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
종
human
1598201
Raloxifene hydrochloride, United States Pharmacopeia (USP) Reference Standard,
종
human
R1402
Raloxifene hydrochloride, solid,
종
human
Y0001134
Raloxifene hydrochloride, European Pharmacopoeia (EP) Reference Standard,
종
human
E0407
Estramustine sodium phosphate, ,
종
human

Small Molecule - Antagonist

Product Number
설명
종
I4409
Fulvestrant, >98% (HPLC),
종
human
1286650
Fulvestrant, United States Pharmacopeia (USP) Reference Standard,
종
human
Y0001413
Fulvestrant for system suitability, European Pharmacopoeia (EP) Reference Standard,
종
human
Y0001399
Fulvestrant, European Pharmacopoeia (EP) Reference Standard,
종
human
M6383
2-Methoxyestradiol, powder,
종
human

Antibodies

Product Number
설명
종별 반응성
응용분야
MABE290
Anti-Estrogen Receptor β Antibody, clone 9.88, clone 9.88, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunoprecipitation (IP)
western blot
05-824
Anti-Estrogen Receptor β Antibody, clone 68-4, rabbit monoclonal, clone 68-4, Upstate®, from rabbit,
종별 반응성
human
응용분야
immunoprecipitation (IP)
western blot
SAB2702145
Monoclonal Anti-ESR2 antibody produced in mouse, ,
종별 반응성
human, monkey, mouse
응용분야
ChIP
dot blot
flow cytometry
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
SAB4301494
Anti-phospho-Estrogen Receptor-β (pSer105) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
HPA068406
Anti-Esr2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
설명
종
E8750
α-Estradiol, powder, ≥98% (TLC),
종
human, rat
E1024
Estradiol, meets USP testing specifications,
종
human, mouse, rat
E2758
β-Estradiol, BioReagent, powder, suitable for cell culture,
종
human, mouse, rat
E2257
β-Estradiol, powder, γ-irradiated, suitable for cell culture,
종
human, mouse, rat
E1132
β-Estradiol, analytical standard,
종
human, mouse, rat

esiRNA

Product Number
설명
종
EHU900081
MISSION® esiRNA, targeting human ESR2,
종
human