E0407

Estramustine sodium phosphate

• 동의어(들): Estra-1,3,5(10)triene-3,17ß-diol 3-[N,N-bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate) sodium salt, Estradiol 3-bis(2-chloroethyl)carbamate 17-(dihydrogen phosphate) sodium salt
• 실험식(Hill 표기법): C₂₃H₃₀Cl₂NNa₂O₆P
• CAS Number: 52205-73-9
• Molecular Weight: 564.35
• EC Number: 257-735-7
• MDL number: MFCD00866320
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329798968
• NACRES: NA.28

속성

• 분석: ≥85.0% (HPLC)
• Quality Level: 100
• 양식: powder
• solubility: H₂O: 50 mg/mL
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: [H][C@]12[C@@]([C@@](CC[C@@H]3OP([O-])([O-])=O)([H])[C@]3(C)CC2)([H])CCC4=C1C=CC(OC(N(CCCl)CCCl)=O)=C4.[Na+].[Na+]
• InChI: 1S/C23H32Cl2NO6P.2Na/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30;;/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30);;/q;2*+1/p-2/t18-,19-,20+,21+,23+;;/m1../s1
• InChI key: IIUMCNJTGSMNRO-VVSKJQCTSA-L
• 유전자 정보: human ... ESR2(2100)

설명

생화학적/생리학적 작용

Estradiol mustard prodrug which binds estradiol receptors irreversibly. Alkylating compound used as an antineoplastic agent against prostate cancer. Depolymerizes microtubules by binding to microtubule associated proteins (MAPs).

Estradiol mustard prodrug, which binds estradiol receptors irreversibly. Highly effective in treatment of advanced metastatic prostate cancer. Depolymerizes microtubules by binding to microtubule associated proteins (MAPs).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves