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Merck

ESR1

estrogen receptor 1

동의어:
ER, ESR, ESRA, ESTRR, Era, NR3A1
:
UniProtKB ID:
Clone ID:
  • Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
  • Mouse(13982) estrogen receptor 1 (alpha)
  • Rat(24890) estrogen receptor 1
  • Goat(100860768) estrogen receptor 1
  • sheep(443228) estrogen receptor 1
  • domestic guinea pig(100713276) estrogen receptor 1
  • Zebrafish(259252) estrogen receptor 1
  • dog(403640) estrogen receptor 1
  • cow(407238) estrogen receptor 1
  • Horse(791249) estrogen receptor 1
  • domestic cat(552888) estrogen receptor 1
  • chicken(396099) estrogen receptor 1
  • Thale Cress(837856) ethylene-responsive transcription factor ESR1

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Small Molecule - Activator

제품 번호
설명
4-Phenylazophenol, 98%,
human
β-Nicotinamide adenine dinucleotide, pkg of 10 mg (per vial),
human
β-Nicotinamide adenine dinucleotide hydrate, ≥95% (HPLC),
human
trans-Stilbene, 96%,
human, rat
β-Nicotinamide adenine dinucleotide lithium salt from Saccharomyces cerevisiae, ≥95%,
human

Small Molecule - Agonist

제품 번호
설명
Estradiol cypionate, United States Pharmacopeia (USP) Reference Standard,
human
Estropipate, United States Pharmacopeia (USP) Reference Standard,
human
Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Estradiol, United States Pharmacopeia (USP) Reference Standard,
human
Estropipate, ≥98% (HPLC), powder,
human

Small Molecule - Allosteric Modulator

제품 번호
설명
Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard,
human
Tamoxifen, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
human
Tamoxifen, analytical standard,
human
Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,
human
Tamoxifen citrate, British Pharmacopoeia (BP) Reference Standard,
human

Small Molecule - Antagonist

제품 번호
설명
3-tert-Butylphenol, 99%,
mouse
2-tert-Butylphenol, 99%,
mouse
Zearalenone, fungal mycotoxin,
mouse
Atrazine, analytical standard,
mouse
4-tert-Octylphenol, 97%,
mouse

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-phospho-Estrogen Receptor alpha (Ser118) Antibody, clone NL44, rabbit monoclonal, clone NL44, Upstate®, from rabbit,
종별 반응성
human
응용분야
western blot
Anti-phospho-Estrogen Receptor-α (pSer167) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-ESR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-ESR1 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-ESR1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, rabbit
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Biphenyl, ≥99%,
human
Biphenyl, ReagentPlus®, 99.5%,
human
Bicyclohexyl, 99%,
human
4,4′-Dihydroxybiphenyl, 97%,
human
4′-Hydroxy-4-biphenylcarbonitrile, 97%,
human

Small Molecule - Ligand

제품 번호
설명
4-Hydroxyestradiol, ,
rat, human
Progesterone, VETRANAL®, analytical standard,
human
Tamoxifen, ≥99%,
human, rat
Progesterone, γ-irradiated, BioXtra, suitable for cell culture,
mouse, human, rat
Progesterone, ≥99%,
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
α-Estradiol, powder, ≥98% (TLC),
human, rat
Medroxyprogesterone 17-acetate, ≥97% (HPLC),
human, rat
Estradiol, meets USP testing specifications,
human, mouse, rat
β-Estradiol, ≥98%,
human, mouse, rat
Progesterone-Water Soluble, powder, BioReagent, suitable for cell culture,
mouse, human, rat

Proteins

제품 번호
설명
Estrogen Receptor-α human, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human ESR1,
human