CASP9
caspase 9, apoptosis-related cysteine peptidase
동의어:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
종:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), Zebrafish casp9 (492763), dog CASP9 (487432), Horse CASP9 (100054331), cow CASP9 (100140945), domestic cat CASP9 (768260), chicken CASP9 (426970), domestic guinea pig Casp9 (100714954) ...더
UniProtKB ID:
Clone ID:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-CASP9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP9 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CASP9 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
western blot
Anti-CASP9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Caspase 9 Antibody, proform & lg. subunit, Chemicon®, from rabbit,
종별 반응성
human, mouse
응용분야
western blot
Small Molecule - Inhibitor
Proteins
제품 번호
설명
종
Caspase 9 human, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous solution, >2,000 units/mg protein,
종
human
esiRNA
Small Molecule - Substrate
제품 번호
설명
종
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
종
mouse, rat, human